abstract：:The objective of the study was to evaluate synovial tissue receptor activator of nuclear factor-κβ ligand (RANKL) and osteoprotegerin (OPG) as biomarkers of disease activity, progressive joint damage, and therapeutic response, during cytokine blockade in rheumatoid arthritis (RA). Patients with active RA entered a ran...

journal_title：Rheumatology international

authors： Rooney T,Edwards CK 3rd,Gogarty M,Greenan L,Veale DJ,FitzGerald O,Dayer JM,Bresnihan B

更新日期：2010-11-01 00:00:00

abstract：:We describe a typical case of a patient with remitting seronegative symmetrical synovitis and pitting edema (RS(3)PE) syndrome. He underwent a successful clinical course monitored by serologic variables and radiographic methods. Serum levels of interleukin-6 (IL-6), vascular endothelial growth factor (VEGF), matrix me...

journal_title：Rheumatology international

authors： Kawashiri SY,Nakano M,Kawakami A,Eguchi K

更新日期：2010-11-01 00:00:00

abstract：:CD4(+) T cells from patients with systemic lupus erythematosus (SLE) exhibit increased expression of various proteins contributing to defective function of CD4(+) T cells. We evaluated the transcript and protein levels of perforin (PRF1) in CD4(+) T cells from SLE patients (n = 41) and healthy individuals (n = 34). Th...

journal_title：Rheumatology international

authors： Kozłowska A,Hrycaj P,Łącki JK,Jagodziński PP

更新日期：2010-11-01 00:00:00

abstract：:A 47-year-old woman who had been treated for systemic lupus erythematosus (SLE) with myasthenia gravis (MG) was admitted to our hospital with acute onset of severe anemia after administration of isoniazid. Pure red cell aplasia (PRCA) was confirmed by elevated serum iron levels, reticulocytopenia and bone marrow aspir...

journal_title：Rheumatology international

authors： Nakamura H,Okada A,Kawakami A,Yamasaki S,Ida H,Motomura M,Imanishi D,Eguchi K

更新日期：2010-11-01 00:00:00

abstract：:The prevalence of Takayasu's arteritis (TA) varies greatly among world populations, and little is known about this disease in Eastern Mediterranean Arab populations. We conducted a retrospective chart review of patients diagnosed with TA from 1996 to 2008 at a single large referral center in Jordan. Eight patients (se...

journal_title：Rheumatology international

authors： Mustafa KN,Hadidy A,Sweiss NJ

更新日期：2010-09-01 00:00:00

abstract：:Objective of the study is to investigate how compliance during the first year of methotrexate (MTX) treatment in rheumatoid arthritis (RA) is influenced by the patients' perception of the necessity for and concern about MTX, the patients' functional disability, and the dose of MTX. A total of 126 RA patients completed...

journal_title：Rheumatology international

authors： de Thurah A,Nørgaard M,Harder I,Stengaard-Pedersen K

更新日期：2010-09-01 00:00:00

abstract：:The aim was to evaluate the relative importance of the 20 functions assessed by patients to produce the Health Assessment Questionnaire's Disability Index (HAQ-DI). A systematic sample of 242 rheumatoid arthritis patients was drawn. Altogether 179 subjects returned acceptably filled questionnaire including perceived r...

journal_title：Rheumatology international

authors： Tuominen R,Möttönen T,Suominen C,Vahlberg T,Tuominen S

更新日期：2010-09-01 00:00:00

abstract：:Some infectious, rheumatic, allergic diseases, and malignancies have been associated with leucocytoclastic vasculitis (LCV). LCV and cancer occur most frequently in patients with hematological malignancies such as lymphomas and leukemias. There have been a few prior cases reported of LCV associated with renal cell car...

journal_title：Rheumatology international

authors： Hong YH

更新日期：2010-08-01 00:00:00

abstract：:Gender may produce different characteristics in the manifestation of systemic lupus erythematosus (SLE). The present study investigated the influence of gender on clinical, laboratory, autoantibodies and histopathological classes of lupus nephritis (LN). As much as 81 patients diagnosed with SLE (ACR criteria) and act...

journal_title：Rheumatology international

authors： de Carvalho JF,do Nascimento AP,Testagrossa LA,Barros RT,Bonfá E

更新日期：2010-08-01 00:00:00

abstract：:The aim of this study was to investigate the prevalence, predictors and radiological findings of primary Sjögren's syndrome (pSS)-associated lung involvement. This retrospective cohort study included 123 patients with demographic, clinical, laboratory and radiological data who were diagnosed with pSS. Lung involvement...

journal_title：Rheumatology international

authors： Yazisiz V,Arslan G,Ozbudak IH,Turker S,Erbasan F,Avci AB,Ozbudak O,Terzioglu E

更新日期：2010-08-01 00:00:00

abstract：:This study was performed to investigate the frequency of human leukocyte antigen (HLA)-B27 in Chinese patients with suspected of ankylosing spondylitis (AS) and to assess the clinical significance of HLA-B27 typing. A total of 1,016 patients suspected of AS were classified into six groups based on one major AS-related...

journal_title：Rheumatology international

authors： Liu X,Li YR,Hu LH,Zhou ZM,Chen FH,Ning Y,Yao QF

更新日期：2010-08-01 00:00:00

abstract：:The expressions of some terminal glycotopes of synovial immunoglobulins G, A, and M were analysed in relation to rheumatoid arthritis (RA) progression defined according to early and advanced radiological changes in patients' hands. The relative amounts of terminal monosaccharides were determined by lectin-immunoblotti...

journal_title：Rheumatology international

authors： Kratz EM,Borysewicz K,Katnik-Prastowska I

更新日期：2010-08-01 00:00:00

abstract：:Uveitis is an important component of many rheumatic diseases. The main causes of recurrent uveitis are seronegative spondylarthropathies and Behçet's disease. We describe a rare case of Henoch Schönlein vasculitis (HSV) along with multiple recurrences of acute anterior uveitis. In cases of skin rash and recurrent ante...

journal_title：Rheumatology international

authors： Erer B,Kamali S,Cingu K,Kilicaslan I,Gul A,Inanc M,Aral O,Tugal-Tutkun I

更新日期：2010-08-01 00:00:00

abstract：:Leg ulcers are a manifestation of antiphospholipid syndrome (APS), and characteristically respond poorly to treatment. Because the similar findings both clinical and pathological to pyoderma gangrenosum (PG), we treated these patients with a combination of immunosuppression (steroids, azathioprine or cyclosporine), ac...

journal_title：Rheumatology international

authors： Cañas CA,Durán CE,Bravo JC,Castaño DE,Tobón GJ

更新日期：2010-07-01 00:00:00

abstract：:We studied the relationships between physician-assessed damage, severity and activity in a large, multicentre systemic sclerosis (SSc, scleroderma) cohort. We hypothesized that there is a relationship between disease activity and severity and damage, but that severity would be more strongly related to damage. A total ...

journal_title：Rheumatology international

authors： Fan X,Pope J,Canadian Scleroderma Research Group.,Baron M

更新日期：2010-07-01 00:00:00

abstract：:Primary osteoarthritis (OA) is a multifactorial disease with several genetics factors involved. The COL2A1 gene is of particular interest because it encodes for the most abundant protein in articular cartilage. The aim was to evaluate the association of COL2A1 gene polymorphism with OA of the knee in Mexican Mestizo p...

journal_title：Rheumatology international

authors： Gálvez-Rosas A,González-Huerta C,Borgonio-Cuadra VM,Duarte-Salazár C,Lara-Alvarado L,de los Angeles Soria-Bastida M,Cortés-González S,Ramón-Gallegos E,Miranda-Duarte A

更新日期：2010-06-01 00:00:00

abstract：:Macrophage activation syndrome (MAS) is a clinical syndrome caused by an excessive proliferation of T lymphocytes and well-differentiated macrophages; an entity distinct from malignant histiocytosis. Although rheumatologic conditions are the common cause of MAS, a wide range of infections are also seen to cause MAS. W...

journal_title：Rheumatology international

authors： Dass R,Barman H,Duwarah SG,Choudhury V,Jain P,Deka NM,Murari M

更新日期：2010-06-01 00:00:00

abstract：:Macrophagic myofascitis (MMF) is an unusual inflammatory myopathy characterized by muscle infiltration by macrophages and lymphocytes. Here, we describe a case of MMF which is associated with rheumatoid arthritis. A 53-year-old Japanese rheumatoid arthritis (RA) patient presented with focal tenderness of lower extremi...

journal_title：Rheumatology international

authors： Migita K,Ueda-Nakata R,Masuda T,Miyashita T,Koga T,Izumi Y,Ichinose K,Ezaki H,Ito M,Motomura M,Eguchi K

更新日期：2010-05-01 00:00:00

abstract：:Neuropathic arthropathy (NA), known as Charcot neuroarthropathy, is a chronic, degenerative arthropathy and is associated with decreased sensory innervation. Numerous causes of this arthropathy have been described. Neuropathic joint, although first described by Charcot in tabes dorsalis in 1868, has subsequently been ...

journal_title：Rheumatology international

authors： Nacir B,Arslan Cebeci S,Cetinkaya E,Karagoz A,Erdem HR

更新日期：2010-05-01 00:00:00

abstract：:Osteoporosis has become an increasingly recognized complication among patients with chronic liver disease (CLD). The aim of the present study was to assess the prevalence and risk factors of osteoporosis in patients with CLD (primary biliary cirrhosis and chronic viral hepatitis B or C patients) in comparison with a g...

journal_title：Rheumatology international

authors： Wariaghli G,Mounach A,Achemlal L,Benbaghdadi I,Aouragh A,Bezza A,El Maghraoui A

更新日期：2010-05-01 00:00:00

abstract：:We report a case of an association of four autoimmune diseases in a 15-year-old girl and we discuss the etiopathogenic of this association and difficulties of treatment. ...

journal_title：Rheumatology international

authors： Zeglaoui H,Landolsi H,Mankai A,Ghedira I,Bouajina E

更新日期：2010-04-01 00:00:00

abstract：:Pancreatitis is a relatively rare but severe manifestation in systemic lupus erythematosus (SLE) patients. We report a case of a 39-year-old woman with previous SLE diagnose treated with prednisone and mycophenolate mofetil who developed an acute pancreatitis complicated by pancreatic pseudocysts within the context of...

journal_title：Rheumatology international

authors： Cairoli E,Pérez G,Briva A,Cancela M,Alonso J

更新日期：2010-03-01 00:00:00

abstract：:Elderly often have Heberden nodes (HN) and Bouchard nodes (BN) that may affect finger dexterity. The aim of this cross-sectional study was to assess an effect of HN and BN on finger dexterity of the elderly. The nine-hole peg test was used for dexterity measurement in 200 elderly with HN and/or BN. Mean age was 68.6 +...

journal_title：Rheumatology international

authors： Kitisomprayoonkul W,Promsopa K,Chaiwanichsiri D

更新日期：2010-02-01 00:00:00

abstract：:Antibodies to citrullinated proteins and rheumatoid factor (RF) are widely used in patients with rheumatoid arthritis (RA) and the antibodies to citrullinated proteins appear to be the most specific markers of the disease. The objective was to compare the diagnostic performance of the anti-cyclic citrullinated peptide...

journal_title：Rheumatology international

authors： Aflaky E,Shenavandeh S,Ashraf MJ

更新日期：2010-02-01 00:00:00

abstract：:We report a case of sudden onset of late infection after TKA inflamed by anti-TNFalpha therapy, Infliximab, in a 54-year-old woman with RA. Infliximab therapy was started 3 years and 8 months after TKAs as a result of multiple arthritides showing high inflammation of RA. One week after the third administration of Infl...

journal_title：Rheumatology international

authors： Yurube T,Takahi K,Owaki H,Fuji T,Kurosaka M,Doita M

更新日期：2010-01-01 00:00:00

abstract：:The aim of the study is to study the relationship between androgen levels and bone mineral density (BMD) in elderly Arab males. Forty-five elderly Arab males underwent Dual X-ray absorptiometry for measurement of BMD. The outcomes were defined as per WHO description. Assays for testosterone (T), gonadotropins (LH and ...

journal_title：Rheumatology international

authors： Al Attia HM,Jaysundaram K,Saraj F

更新日期：2010-01-01 00:00:00

abstract：:Abstract A 66-year-old woman showing renal dysfunction with elevated serum alkaline phosphatase and anti-SS-A antibody was admitted. A labial salivary gland biopsy showing infiltration of mononuclear cells and positive anti-SS-A antibody with sicca symptoms led to a diagnosis of primary Sjögren’s syndrome (SS). Fancon...

journal_title：Rheumatology international

authors： Nakamura H,Kita J,Kawakami A,Yamasaki S,Ida H,Sakamoto N,Furusu A,Eguchi K

更新日期：2009-12-01 00:00:00

abstract：:Thrombocytosis is well described in children with Kawasaki disease (KD). We describe six children with KD who had thrombocytopenia at disease onset. This is an unusual finding and has clinical implications in the diagnosis of this condition. ...

journal_title：Rheumatology international

authors： Singh S,Gupta D,Suri D,Kumar RM,Ahluwalia J,Das R,Varma N

更新日期：2009-12-01 00:00:00

abstract：:The objectives of this study are to evaluate the prevalence of radiographic hand osteoarthritis (OA) in Chuvashian community-based sample and its associations with age, sex, body mass index (BMI), smoking, and alcohol consumption. The study population was comprised of Chuvashians (443 males, age 47.4 ± 17.0 years and ...

journal_title：Rheumatology international

authors： Kalichman L,Kobyliansky E

更新日期：2009-11-01 00:00:00

abstract：:Autoimmune diseases (AID) are caused by the loss of immunological tolerance against self-antigens. The deoxyribonuclease I (DNASE1) gene seems to participate in the genetic susceptibility of some AID. In fact, two mutations were reported among systemic lupus erythematosus (SLE) patients from Japan and Spain (the 172 A...

journal_title：Rheumatology international

authors： Belguith-Maalej S,Hadj-Kacem H,Kaddour N,Bahloul Z,Ayadi H

更新日期：2009-11-01 00:00:00

abstract：:Adult-onset Still's disease (AOSD) is a systemic inflammatory disease in which a variety of thrombotic events may occur. However, to our knowledge, portal vein thrombosis (PVT), a potential cause of gastrointestinal bleeding, has not been described in the English literature. A previously well 47-year-old man diagnosed...

journal_title：Rheumatology international

authors： Morita H,Nishiwaki H,Nagayama Y,Yoshimura A

更新日期：2009-10-01 00:00:00

abstract：:PADI4 that catalyzes the conversion of peptidylarginine to citrulline is associated with rheumatoid arthritis in some populations. The current study investigated the expressions of PADI4 in synovial fluid of RA (n = 73), osteoarthritis (OA, n = 96) and ankylosing spondylitis (AS, n = 32) using ELISA and western blotti...

journal_title：Rheumatology international

authors： Chang X,Zhao Y,Sun S,Zhang Y,Zhu Y

更新日期：2009-10-01 00:00:00

abstract：:Non-tuberculous mycobacteria (NTM) are an unusual cause of osteomyelitis in immunocompetent children. Diagnosis is often difficult due to the paucity of clinical symptoms and a subtle course of the disease. NTM comprise a group of about 91 identified species of environmental mycobacteria that cause infections most fre...

journal_title：Rheumatology international

authors： Breda L,de Michele G,Nozzi M,De Sanctis S,Di Marzio D,Chiarelli F

更新日期：2009-10-01 00:00:00

abstract：:The objective of this study is to investigate the clinical markers of life-threatening Pneumocystis pneumonia (PCP) in patients with collagen vascular diseases (CVD). The patients who contracted Pneumocystis jeroveccii were retrospectively selected from our medical charts and conditions related to the patients' death ...

journal_title：Rheumatology international

authors： Aoki Y,Iwamoto M,Kamata Y,Nagashima T,Yoshio T,Okazaki H,Minota S

更新日期：2009-09-01 00:00:00

abstract：:The aim of this study was to compare clinical symptoms, perceived health status, health resource use and psychosocial features in fibromyalgia (FM) patients at different health care levels. A total of 315 participants were recruited from primary care (PC) (n=101) and rheumatology settings (RS) (n=214). Subjects comple...

journal_title：Rheumatology international

authors： Boyer AL,Mira Pastor MA,Calatayud NP,Lopez-Roig S,Cantero Terol MC

更新日期：2009-08-01 00:00:00

abstract：:In the present study, we have investigated comparatively the inflammatory response of patients with active and inactive osteoarthritis. The sera from 31 healthy individuals, 37 patients with active OA, and 19 patients with inactive OA were assayed for TNF-alpha, IL-6, sRANKL, RANTES, and MRP8 using ELISA in order to e...

journal_title：Rheumatology international

authors： Toncheva A,Remichkova M,Ikonomova K,Dimitrova P,Ivanovska N

更新日期：2009-08-01 00:00:00

abstract：:Among the clinical manifestations of systemic lupus erythematosus is an arthropathy, which is usually non-erosive. In many cases, the joint involvement is mild. A subset of patients has deforming, non-erosive Jaccoud's arthropathy, and a minority have an arthropathy with clinical findings similar to rheumatoid arthrit...

journal_title：Rheumatology international

authors： Pipili C,Sfritzeri A,Cholongitas E

更新日期：2009-08-01 00:00:00

abstract：:The study includes a case report and a literature review. The main objective of this study is to present a case of spondylodiscitis due to a fungal pathogen, Blastoschizomyces capitatus and to review the published literature on this emergent fungus in etiology of spondylodiscitis, and osteomyelitis. Osteoarticular inv...

journal_title：Rheumatology international

authors： Celik AD,Ozaras R,Kantarcioglu S,Mert A,Tabak F,Ozturk R

更新日期：2009-08-01 00:00:00

abstract：:We report on a 7-month-old infant with Kawasaki disease (KD) whose only manifestations were high-grade fever of 7 days duration, "non-toxic look" and "extreme irritability", thereby not meeting the criteria for the classical or the atypical form of the disease. The diagnosis was confirmed by the demonstration of a sol...

journal_title：Rheumatology international

authors： Thapa R,Chakrabartty S

更新日期：2009-07-01 00:00:00

abstract：:Patients with rheumatoid arthritis (RA) are at increased risk of low bone density and fractures. This study identifies predictors of initiation of dual energy X-ray absorptiometry (DXA) testing in RA. We identified RA patients from the CORRONA registry with >or=1 year follow-up without reported DXA at study entry. The...

journal_title：Rheumatology international

authors： Aizer J,Reed G,Onofrei A,Harrison MJ

更新日期：2009-06-01 00:00:00